Probabilistic models of biological enzymatic polymerization

1 D Models for Enzymatic Biological Fuel Cells

61 (continued on next page) can be estimated. This process requires not only a model for transport in the system, but also a model for the kinetics, in terms of the relationship between driving force and the kinetically-controlled rate. Similarly, the desire to build real-world systems with bioelectrocatalysts requires engineering approaches to predict realworld performance, including the effec...

Statistical Approaches and Rich Probabilistic Models of Biological Regulation

Acknowledgements This dissertation would not have been possible without the help and support from many people to whom I am greatly indebted. First of all, I thank my advisor, Bud Mishra for his support, encouragement and collaboration. It is Bud who introduced me to the computational world, and guided me into the exciting interdisciplinary field of computational biology. He has taught me the va...

Polymersome nanoreactors for enzymatic ring-opening polymerization.

Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization of lactones in water. It is shown that the monomers 8-octanolactone and dodecalactone yield oligomers with this polymersome system. It is also observed that the polymerization a...

Highly efficient enzymatic catalysis for cyclocarbonate polymerization

In this study, we developed a metal-free biosynthetic strategy of enzymatic polymerization to fabricate aliphatic poly(pentamethylene carbonate) (PPMC). Novozym-435 lipase showed considerably high catalytic efficiency, and high molecular weights (Mn) of up to 6.0 104 g mol 1 were readily achieved through the ring-opening polymerization of cyclobis(pentamethylene carbonate). The reaction paramet...

Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids